Israeli police have raided al-Aqsa mosque's compound, clashing with Muslim worshippers and arresting Palestinian protesters.
Al Jazeera has learnt that the clashes erupted on Sunday after Israeli police tried to enter the compound in occupied Jerusalem's Old City.
The site is known to Jews as the Temple Mount and is revered by Muslims as al-Haram al-Sharif (the Noble Sanctuary), comprising al-Aqsa mosque and the Dome of the Rock.
At least 10 people were injured and another 15 detained, Al Jazeera's correspondent in Jerusalem said.
Israeli police put the number of arrests at 12.
Early on Sunday, Israel police deployed extra troops after calls for demonstrations around the holy site.
The Palestinian calls came amid rumours that rightwing Jewish activists were planning to gather at al-Aqsa compound.
The rumours circulated after a fringe Israeli group, the Organisation for the Defence of Human Rights on the Temple Mount, called on Jews to gather at the mosque compound as well as the adjacent Western Wall.
Palestinian officials said the Israeli police closed off the compound to visitors, leaving hundreds of worshippers inside.
Jivara al-Budairi, Al Jazeera's correspondent in Jerusalem, said: "Clashes between Palestinians and the Israeli police spread to the Old City neighbourhoods of Bab Hutta, Bab al-Majlis and Aqabat al-Tkiye.
She said the injured could not be moved out of the compound because of the Israeli police siege.
She said the violence in the Old City erupted after the Israeli police fired tear gas and stun grenades at Palestinian students and youths in the area.
The youths retaliated by throwing stones at the soldiers.
Columns of black smoke could be seen rising from areas close to the mosque compound, our correspondent said.
It seems that Palestinian youths set ablaze tyres in areas where Israeli police and army forces were heavily deployed, she said.
A large number of Palestinians began a march from the Old City towards al-Aqsa mosque, she said.
The neighbourhood's merchants have, meanwhile, announced a comprehensive strike and closed all shops, al-Budairi said.
Micky Rosenfeld, the Israeli police spokesman, said the raid and arrests took place after Palestinian youths threw stones and a petrol bomb at a police patrol near the mosque.
Shmuel Ben-Ruby, the Jerusalem police spokesman, admitted that security forces used stun grenades to disperse the demonstrators.
He accused the protesters of pouring oil on the ground to make the police forces slip, and of hurling a firebomb.
Ben-Ruby said police did not enter mosque itself.
But Kamal Khatib, a spokesman for the Israeli Arab Islamic Movement, which has been at the forefront of recent al-Asa demonstrations, blamed Israeli police for the clashes.
"The police always excuse their attacks by saying that the worshippers threw stones," he told the AFP news agency.
"It is clear they just want to justify their crimes."
Khatib further accused the police of stopping buses filled with Muslim worshippers in northern Israel in a bid to prevent them from reaching Jerusalem.
Describing the situation to Al Jazeera, Sheikh Muhammad Hussein, the mufti of Jerusalem, said: "Israeli forces entered the compound from the Maghareba and Silsila gates.
"The forces cordoned off the compound, preventing all Muslims from entering the mosque.
"The situation is extremely serious, and I expect it to escalate.
"The Israelis have beaten the mosque's guards and staff, as well as worshippers, including women.
"I was personally prevented from entering the mosque. They are preventing us by force from reaching the mosque, where Sheikh Abdul Azeem Salhab, head of the endowments council, several endowments department staff and a number of worshippers are at present under siege.
"We are besieged in al-Haram al-Sharif yard, while they are trapped inside al-Aqsa mosque.
“A large number of Israeli policemen and security officers are deployed inside al-Haram al-Sharif. They have detained most of the Palestinian worshippers who were inside the compound."
Tensions exploded into violence on September 27, when Palestinians hurled rocks at a group of visitors whom they suspected of being rightwing Jewish extremists.
Israel captured the compound from Jordan in the 1967 Middle East War and it has since served as a symbol of the two sides' competing claims to Jerusalem.
Day-to-day administration of the site remains in Muslim hands.
In September 2000, the second Palestinian uprising, or intifada, erupted after Ariel Sharon, a rightwing politician who went on to become Israel's prime minister, visited the site.
Source: Al Jazeera and agencies